Taxifolin is not mutagenic and low toxic compared to the related compound quercetin. It acts as a potential chemopreventive agent by regulating genes via an ARE-dependent mechanism.
Taxifolin has shown to inhibit the ovarian cancer cell growth in a dose-dependent manner. There is also a strong correlation between the antiproliferative effects of dihydroquercetin derivatives on murine skin fibroblasts and human breast cancer cells.
The capacity of taxifolin to stimulate fibril formation and promote stabilization of fibrillar forms of collagen can be used in medicine. Also taxifolin inhibited the cellular melanogenesis as effectively as arbutin, one of the most widely used hypopigmenting agents in cosmetics. However, arbutin acts as quercetin extremely mutagenic, carcinogenic and toxic.
Taxifolin enhance also the efficacy of conventional antibiotics like levofloxacin and ceftazidime in vitro, which have potential for combinatory therapy of patients infected with methicillin-resistant Staphylococcus aureus.
1).Taxifolin’s biological functions and applications in medical science ; taxifolin can decrease headache of hypertensive patients with atherosclerosis , coordination disturbance , and also have positive effect on lipid metabolism and improve cerebral microcirculation .
2).For patients with ischemic heart disease after aorta-coronary shunting surgery , taxifolin can improve microcirculation , central and peripheral hemodynamic , blood oxygenation , and psychological mood .
3)For patients with chronic venous insufficiency , taxifolin can positively changes in hemodynamic indices , rheological blood parameters and normalization of cholesterol metabolism .
4)For patients with arterial hypertension of the II & III degree , taxifolin can decrease in blood viscosity , increase in the time of erythrocyte aggregation , decrease in blood pressure , ncrease in systolic index , decrease in the levels of the primary and secondary products of lipid peroxidation .
5).For patients with ischemic heart disease , taxifolin can positive effects on the hemorheological status and significantly decreased anginal episodes.
6).For patients with diabetes mellitus , taxifolin can decrease in HbAlx levels and improved sensitivity to insulin without side effects .
7).For male patients with chronic pulmonary obstructive disease , taxifolin can normalize indices of tissue and organs’ microcirculation , increase blood oxygenation , improve rheological blood parameters , increase tolerance to physical exercise , and improve functioning of the respiratory and cardiovascular systems without no side effects .
8).Recently, scientific research has found that taxifoilin can treat and prevent skin cancer .
1).Applied in pharmaceutic.
2).Applied in health product field.
3). Applied in cosmetics
Packaging & Shipping
Packaging and Shipping :
Packaging:1 kg/bag, 25 KGS/drum, with double layers plastic bags in, external use cardboard drums.
Preservation Methods:In a cool and dry, avoid light, avoid high temperature place.
Shelf life:24 months if proper stock
Xi'an Hao Xuan Biological Technology Co., Ltd. founded in 2008, mainly engaged in natural plant active ingredients and pharmaceutical intermediates R&D, production and sales. The company has modern production equipment in the domestic advanced level. Annually, herbs processing capacity about 1,000 tons, finished product capacity of 2,000 kg. Be widely used in medicine, chemicals, food, health products and other fields. As a gold supplier, a new production line was founded in 2014. In 2015, the factory could customize high-content monomer products. We have got Kosher certification in 2016 and SC certification in 2017.